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Ceftin 250mg, 500mg
Ceftin pill

Ceftin is known as a cephalosporin antibiotic to treat bacterial infections. It means that the drug acts on the walls of bacteria cells. The active ingredient is CEFUROXIME. Ceftin disrupts the synthesis of peptidoglycan proteins, which leads to the elimination of the bacterial cell. The tablets are oblong and produced in dosages 250 and 500 mg.

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How is Ceftin (CEFUROXIME) absorbed and then excreted by the body?

After ingestion, the drug absorbs in the small intestine, hydrolyzes, and enters the bloodstream. Absorption occurs quickly, especially after a meal. The maximum concentration is observed after 3 hours, binding to proteins up to 50%. Ceftin crosses the blood-brain barrier and does not undergo biotransformation. Excretion occurs in the kidneys, and the half-life is one and a half hours.

For what syndromes and diseases is Ceftin (CEFUROXIME) prescribed?

Ceftin is prescribed to treat the following diseases:
Acute bronchitis and its exacerbation, Bronchiectasis, pleural empyema, lung abscess, otitis media, pharyngitis, tonsillitis, sinusitis, epiglottitis, diseases of the genitourinary system; cystitis, urethritis, asymptomatic bacteriuria, acute and exacerbation of chronic pyelonephritis, infections of the skin, tissues, bones and joints, surgical interventions, as well as Lyme disease in the early stages.

Recommendations before taking Ceftin

Taking the drug is recommended after meals with a bit of water. Ceftin is approved for use in adults, the elderly, and children over 3 months of age.

Dosage regimen

The dosage for adults and children weighing more than 40 kg is from 250 to 500 mg, depending on the disease. For children under 2 years of age, the dosage calculation is 10 mg/kg, over 2 years old is 15 mg/kg.


An overdose of the drug causes disturbances in the nervous system, causing encephalopathy, seizures, and even coma. It is often associated with an incorrectly selected dosage in children with a bodyweight of less than 40 kg and persons with severe renal failure.

Treatment: the concentration of the drug in the blood can be reduced by hemodialysis and peritoneal dialysis.


Ceftin is contraindicated if a patient has an increased reaction to drugs of the cephalosporin group and other beta-lactamases, such as penicillins, carbapenems, Etc.

Is it allowed to use Ceftin during pregnancy and lactation?

Cephalosporins are one of the groups of antibiotics approved for use during pregnancy. However, it is recommended to prescribe the drug under the special supervision of the attending physician, especially in the first trimester of pregnancy and lactation.

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Side effects of Ceftin

Among the side effects, allergic reactions are primarily distinguished, such as itching, rash, urticaria, bronchospasm, erythema, anaphylactic shock, malignant exudative erythema multiforme. Therefore, it is crucial to do an allergy test for taking a new antibiotic.

Among the allergies of the gastrointestinal tract, one can distinguish rumble, diarrhea, nausea, constipation, bloating, abdominal pain, tenesmus, oral ulcers, oral candidiasis, glossitis, enterocolitis, cholestasis, increased activity of liver enzymes (ALT, AST, ALP, LDH ), as well as bilirubin.

Other manifestations of the incompatibility of the drug with the body are dysuria, impaired renal function, itching in the perineum, vaginitis, convulsions, phlebitis, hearing loss.

Side effects from the hematopoietic system: anemia, neutropenia, leukopenia, decreased platelets, agranulocytosis, prolongation of PT, decreased hematocrit.

Interactions of Ceftin with other drugs

The concentration of cefuroxime rises if used in conjunction with diuretics. The half-life also increases.

The risk of development of nephrotoxic effects increases If antibiotics from the aminoglycoside group (e.g., diuretics, probenecid) are used simultaneously.

Drugs such as proton pump inhibitors, namely H2 receptor blockers, reduce the bioavailability and the antibiotic's effect.

The joint use of non-steroidal anti-inflammatory drugs increases the risk of bleeding.

Ceftin reduces the effectiveness of combined oral contraceptives, affecting the intestinal microflora and disrupting estrogen reabsorption.

It is necessary to use the glucosidase and hexokinase methods to determine the blood glucose level since the ferrocyanide method can give a false-negative result when taking cefuroxime.

Special instructions before prescribing Ceftin

Before prescribing the drug, it is imperative to conduct an allergy test and collect an allergic anamnesis.

It is also necessary to determine what drugs the patient uses to monitor renal function due to nephrotoxicity, especially when taking the drug in high dosages.

Long-term use of an antibiotic leads to the development of candidiasis, and in this case, antifungal drugs are necessary.

Antibiotics can cause pseudomembranous colitis; therefore, a thorough examination is necessary if diarrhea develops after taking cefuroxime.

The drug can cause dizziness. In this case, the patient should be warned about the precautions when driving.

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Bronchiectasis what is it, and how is it treated?

Bronchiectasis is a congenital or acquired process associated with expansion, deformation, inflammation, infiltration, hardening of more often segmental bronchi, impaired drainage function, the development of atelectasis, emphysema, and respiratory failure.

In simple words, Bronchiectasis is the expansion and deformation of the segmental parts of the bronchi, caused by destruction or disturbance of neuromuscular tone, depending on the etiology. Depending on the cause, primary (congenital) and secondary (the result of infections, aspiration, lung diseases) are distinguished.

Bronchiectasis is commonly diagnosed among children and young men.

Congenital diseases include diseases that cause a violation of mucociliary clearance. These include cystic fibrosis, Kartagener's syndrome, Young's syndrome, ciliary dyskinesia, L1 antitrypsin deficiency, primary immunodeficiency, Etc.

Acquired Bronchiectasis is associated with complicated infections, such as measles, pneumoconiosis, sarcoidosis, ankylosing spondylitis, aspergillosis, AIDS, Sjogren's syndrome, rheumatoid arthritis, ulcerative colitis, idiopathic pulmonary fibrosis, inhalation of toxic substances, and many others.

According to the deformation of the bronchi themselves, they are distinguished: saccular, spindle-shaped, cylindrical, and mixed forms.

According to the spread of the process, 2 types are distinguished - one-sided and two-sided.

How does this disease proceed?

When a patient visits a doctor, the first complaint will be a prolonged cough with much sputum, especially in the morning. The phlegm is most often purulent, hence the bad breath. The patient may also complain of shortness of breath during exertion, wheezing, and slightly high body temperature. Usually, people with Bronchiectasis are more susceptible to lower respiratory tract infections, which are often recurrent.

The shape of the fingers' nail plates and terminal phalanges can change if there is a long course of the disease. Fingers take the form of drum sticks, and the nail plates look like watch glass. In addition, as a result of the development of Emphysema or Pulmonary Fibrosis, the chest can be deformed.

With a pronounced form of exacerbation, every season, 3-4 times a year, sputum releases from 50 to 200 ml per day.

In severe cases, exacerbations are frequent, and remissions are short-lived. Sputum is released 200 ml or more, most often accompanied by a temperature reaction. Wheezing is better after coughing up phlegm.

Bronchography will help make an accurate diagnosis, which allows the patients to identify the degree of prevalence, form, and localization of Bronchiectasis.

How to prevent disease?

Quit smoking;
Elimination of inhalation of industrial and dust hazards;
Rehabilitation of chronic foci with sinusitis, diseases of the oral cavity and dentition;
Observation by a pulmonologist for chronic lung diseases such as bronchitis, pneumoconiosis, Etc.
Prevention of respiratory infections;
Immunization against measles and whooping cough;
Annual flu vaccination.

What are the complications?

With incorrect and untimely treatment, serious complications appear that affect not only the respiratory system. Complications include hemoptysis and pulmonary hemorrhage, occurring in 20% of cases, as well as the development of spontaneous pneumothorax, abscess, pleural empyema, sepsis, aspiration, pyopneumothorax, cor pulmonale, frequent pneumonia, pleurisy, renal amyloidosis, and chronic respiratory failure.

Treatment with alternative medicine

Undoubtedly, with this disease, the patient will consult a doctor and be examined. If this disease is diagnosed, then compulsory antibiotic therapy is required, among which Ceftin has proven itself well. In addition, auxiliary drugs are prescribed: anti-inflammatory, mucolytics, bronchodilators, immunomodulators, vitamin-mineral complexes, etc.

Additionally, you can use traditional medicine, but only in consultation with your doctor.

The most well-known methods include:

• Once a day, stir 1 tablespoon of badger fat in a glass of hot milk and drink. The course should be no more than 30 days since fat is hefty for the liver and, at the same time, is one of the most beneficial for the bronchopulmonary system.

• You can use plantain juice, black radish, and viburnum. Mix plantain juice with honey in a 2: 1 ratio, take before meals 6 times a day.

• Another method is to use 1 kg of butter and 150 g of crushed propolis. Melt butter, cool to 80 C, add propolis, stirring for 20 minutes at the same temperature. Strain, place in a dark place. Take 60 minutes before meals 3 times a day for 2 months.

• To do herbal inhalations, you need 1 ml of eucalyptus, tincture of ginseng, echinacea, Eleutherococcus. Breathe by inhalation for 5 minutes, 2 times a day. The course lasts 10 days.

• Garlic. Finely chop the head of garlic, mix with a glass of milk. Simmer for 5 minutes, drain. It should be taken 1 spoon 3 times a day.

• Carrot juice. Mix 1 glass of juice with a glass of milk, add 2 tablespoons of lime honey. Leave in a dark place for 7 hours, stirring occasionally. Take 1 spoon 4-5 times a day, preheated.

The following list has a beneficial effect on the respiratory system: anise, licorice root, Icelandic moss, pine and birch buds, aloe, Thermopsis, coltsfoot, licorice root, marshmallow, calendula, and sage.

Nutrition plays an essential role in treating patients. The diet of patients should contain more proteins (up to 150 g), a moderate amount of fats and carbohydrates. In addition, the patient must consume vitamin complexes of vitamins A, C, B1, B2. Vitamin A promotes rapid regeneration of the bronchial mucosa, while others improve protein metabolism and oxidative processes in cells. Limiting salt intake is recommended.

Brief conclusion

In 25-52% of cases, the etiology of bronchiectasis remains unknown. The incidence among children under 14 years of age is considered low in developed countries, at about 0.5 per 100,000 children, while there are 216-2646 cases per 100,000 children in India. From statistics, we see that bronchiectasis is a critical problem, especially among socially disadvantaged countries, where there is a huge population, low hygiene, and poor medical care.

The decrease in FEV1 in BE is 55 ml per year, while in healthy individuals, it is 30 ml. The most unfavorable prognosis is BE against the background of cystic fibrosis. Here, the average survival rate is 35 years.

Today, surgical treatment is actively used - the surgical removal of bronchiectasis, which leads to a complete recovery.

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